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SMZ-TMP Pediatric and alcohol

Result of checker of drug SMZ-TMP Pediatric interaction with alcohol. Whether they can be taken together or this combination is not allowed.

Check result:

SMZ-TMP Pediatric <> Alcohol

Relevance: 01.01.2021

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with alcohol.

Consumer:

Ask your doctor before using trimethoprim together with ethanol. Do not drink alcohol while you are taking trimethoprim. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Check your food and medicine labels to be sure these products do not contain alcohol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Two cases have been reported in which patients on sulfamethoxazole-trimethoprim therapy, after consuming beer, reported flushing, heart palpitations, dyspnea, headache, and nausea (disulfiram - alcohol type reactions). The proposed mechanism is inhibition of acetaldehyde dehydrogenase resulting in acetaldehyde accumulation.

MANAGEMENT: Patients should be alerted to the potential for this interaction, and advised to avoid alcohol while taking sulfamethoxazole-trimethoprim.

References:

Heelon MW, White M "Disulfiram-cotrimoxazole reaction." Pharmacotherapy 18 (1998): 869-70

SMZ-TMP Pediatric

Generic Name: sulfamethoxazole / trimethoprim

Brand Name: Bactrim, Bactrim DS, Bactrim IV, Septra IV, SMZ-TMP DS, Sulfatrim Pediatric, Septra, Sulfatrim, Bethaprim, Cotrim, Uroplus, Uroplus DS, Cotrim DS, Bactrim Pediatric, Bethaprim Pediatric, Sulfatrim Suspension, Cotrim Pediatric, Septra DS

Synonyms: Sulfamethoxazole and trimethoprim, Sulfamethoxazole and Trimethoprim

What is SMZ-TMP Pediatric?